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Despite its benefits, isoflurane does have some drawbacks. The most significant concerns include respiratory irritation, which can lead to coughing or breath-holding during induction, and the risk of postoperative nausea and vomiting. Patients with a history of respiratory issues may also experience compounded effects when using isoflurane. Furthermore, while isoflurane is effecive in maintaining anesthesia, it does not provide analgesic properties on its own, necessitating the use of additional medications to manage pain effectively during and after surgery.


Furthermore, the antioxidant capabilities of PQQ can help mitigate oxidative stress caused by the metabolism of homocysteine—an amino acid often elevated due to low MTHF levels. By supporting each other’s functions, MTHF and PQQ may contribute to better cardiovascular health, cognitive function, and overall resilience against chronic diseases.


 

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Isoflurane is a widely utilized volatile anesthetic agent known for its effectiveness in both human and veterinary medicine. It belongs to the halogenated ether class of anesthetics and is recognized for its relatively low blood-gas partition coefficient, which allows for rapid induction and recovery times, making it a favored choice among anesthesiologists.


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